unclear, a multitude of inhaled organic particles
unclear, but evidence supports a role for both type III andtype IV immune responses.occupational antigens. The exact pathophysiologic mechanismof hypersensitivity pneumonitis remains exaggerated immune response after exposure to a multitude ofinhaled organic particles or related Hypersensitivitypneumonitis is a form of inflammatory lung disease that results from an to the specific hapten results in rapid recruitment andactivation of memory-specific T cells.
dendritic cells, which then migrate to regional lymph nodesand stimulate T cell production. Reexposure have come in direct contact with a halpen. During thesensitization phase, haptens are captured by takes place in two phases, sensitization and elicitation.
Itis usually confined to sites on the skin that Allergiccontact dermatitis is a type IV hypersensitivity reaction. The inflammatoryresponse circulating IgG antibody.completely understood but is believed to be the result oflocalized contact of injected antigen with form at the center of the lesion due to the release ofcytokines. The Arthus reaction mechanism is not begin within one hour of an exposure. Lesions are typicallyred, raised, and inflammed. Ulcers often necrosis, usually in the skin.
It is caused by repeatedlocal exposure to an antigen. Symptoms usually TheArthus reaction is a localized immune complex reaction associated with discretetissue leukotrienes, that are responsible for rhinorrhea, sneezing,nasal itching, and watery eyes. in IgE production. IgE production, in turn, triggers therelease of mediators such as histamine and cells by APCs. In the presence of cellular cytokines, B-cellclass switching occurs, resulting in an increase aeroallergens are inhaled, they are deposited mainly on thenasal mucosa where they are presented to T Theallergic response in allergic rhinitis is located specifically in the nasalmucosa. When cause) of coronary artery disease.
“used in our text to explain etiology is the following,”atherosclerosis often is cited as the etiology (or etiologic agent until tlhe ultimate expression of a disease”Grossman and Porth (2014). A great example “the sequence of cellular and tissue events that take placefrom the time of initial contact with an important to define pathogenesis; not to be confused with theterm etiology. Pathogenesis refers to allergic rhinitis, arthus reaction, contact dermatitis, and hypersensitivitypneumonitis. To begin it is first further classified as one of four types: type I, type II,type III, and type IV. The topics discussed will be In this paper I will be discussing the pathogenesis of several hypersensitivityreactions which are
