Lung Function Tests On Petrol Pump Workers Biology Essay

Introduction: Air pollution from vehicles is an ineluctable portion of urban life. Long term exposure to petrol and diesel exhausts lead to hurtful consequence on respiratory map. In-addition to exposure to risky fumes of vehicles, petrol-pump workers are besides exposed to bluess of gasoline.

Aim & A ; aims: Aim was to analyze alterations in pneumonic maps in petrol-pump workers exposed to petrol/diesel exhausts and comparison alterations with age-matched healthy controls.

Material & A ; Methods: The survey comprised of 150 petrol-pump workers who were categorized into three groups depending on continuance of exposure. Fifty healthy age-matched males served as controls. Each topic ‘s age, smoking wonts, continuance of exposure and wellness conditions were recorded. The pulmonary-function trials were performed at their workplace with Med-spiror. The statistical analysis was done utilizing one-way analysis of variance with post-hoc Meleagris gallopavo.

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Consequences: The consequences showed statistically important diminution in values of FVC, FEV0.5, FEV1, FEV3 and FEF 50 % , FEF 25-75 % in petrol-pump workers. However, diminution in PEFR, MVV, FEF 25 % , FEF 75 % , FEV 0.5 / FVC, FEV1/FVC, FEV3 / FVC was statistically undistinguished.

Decision: Our findings are implicative of inauspicious effects of petrol/diesel exhausts on pneumonic maps.

Cardinal words: Petrol & A ; Diesel exhausts, respiratory map, Pulmonary map trials, Timed critical capacity


Air pollution from vehicles is an ineluctable portion of urban life throughout the universe. Long term exposure to air pollutants leads to hurtful effects on respiratory maps. The quickly multiplying figure of cars in most metropoliss is doing matching addition in air pollution which is a cause of grave concern.

Petrol is a mixture of volatile hydrocarbons, while the Diesel fuel is a distillation of crude oil which contains paraffins, olefines and aromatics. Both gasoline and Diesel undergo burning in car engines and give rise to combustion-derived nano-particles ( CDNP ) . Diesel exhaust atoms are the most common CDNP in urban environmental air. These atoms are extremely respirable and have big surface country where organics can be adsorbed easy. Atoms generated from Diesel fumes are sub-micronic, -by virtuousness of their greater surface area-to-mass ratio- can transport a larger fraction of toxic hydrocarbons and metals on their surface. They can stay airborne for longer clip and sedimentation in greater Numberss and deeper into lungs than larger-sized atoms.

Benzene occurs of course in rough oil and is a component of gasoline. Petrol-pump workers exposed to petrol exhausts exhibit a figure of clinical marks and symptoms. The symptoms are more normally observed in summer, when exposure to gasoline blues is greater because of higher environmental temperature.


This survey was conducted in the Department of Physiology, Govt. Medical College, Amritsar. Subjects comprised of 150 males working in different gasoline pumps. Age, smoking wonts, continuance of exposure, physical position and wellness conditions were recorded through questionnaire. After entering brief history, scrutiny was done as per the Performa attached. The ethical commission clearance and an informed consent of the topics were taken.

Subjects with clinical abnormalcies of vertebral column and thorax, diabetes mellitus, pneumonic TB, bronchial asthma, chronic bronchitis, bronchiectesis, emphysema and malignance, drug nuts, coffin nail tobacco users, baccy chewers and those who had undergone abdominal or chest surgery were excluded from the study.The survey group was categorized harmonizing to the continuance of service at the gasoline pumps which is as under: –


Duration of service

No. of instances


Upto 1 twelvemonth of service



1-5 old ages of service



More than 5 old ages of service


There were 50 controls which comprised of age and sex matched healthy grownup males, non-smokers working in the infirmary as attenders, medical helper and other infirmary forces ( Group IV ) .

The pneumonic map trials were performed at the workplace with Med-spiror ( Recorders and Medicare System, Chandigarh ) . It is a computerized spirometer designed to be used with electromechanical pneumotach. Testing processs were rather simple and non invasive and are harmless to the patients. Merely 2 manoeuvers were required from the topic to roll up all trial informations, a forced critical capacity and maximum voluntary airing.

FVC, FEV 0.5, FEV 1, FEV 3, PEFR, FEF 25-75 % , FEF 25 % , FEF 50 % , FEF 75 % , FEV 0.5/FVC, FEV 1/FVC, FEV3 /FVC, MVV were calculated. All gas volumes were corrected to B.T.P.S ( Body temperature, ambient force per unit area and saturated with H2O vapor ) automatically by the instrument.

The information was analyzed utilizing computing machine package Microsoft Excel Statistical Package of Social Sciences ( SPSS version 10.0 ) . Mean and standard divergence ( SD ) was calculated and reported for quantitative variables. The statistical difference in average value was tested utilizing one manner ANOVA ( analysis of discrepancy ) with post-hoc Meleagris gallopavo. A p-value of & lt ; 0.05 was considered as statistically important.


Table 1: Feature OF THE SUBJECTS




AGE ( old ages ) : topics


28.23 A± 9.21

23.36 A± 2.71

0.24: Nitrogen

HEIGHT ( centimeter ) : topics


164.05 A± 8.13

165.98 A± 8.51

0.46: Nitrogen

WEIGHT ( Kg ) : topics


55.23 A± 8.58

59.36 A± 10.70

0.98: Nitrogen

BSA: topics


1.53 A± 0.11

1.57 A± 0.13

0.77: Nitrogen

P & gt ; 0.05 ; NS- Non important












3.05 A± 0.46

2.77 A± 0.42

2.38 A± 0.61

3.78 A± 0.54

FEV 0.5

1.77 A± 0.65

1.76 A± 0.59

1.27 A± 0.72

2.60 A± 0.32


2.65 A± 0.43

2.55 A± 0.41

1.98 A± 0.77

3.21 A± 0.55


3.04 A± 0.47

2.73 A± 0.42

2.36 A± 0.68

3.59 A± 0.70


6.03 A± 1.88

6.20 A± 1.64

5.12 A± 2.84

7.91 A± 1.27

FEF 25-75 %

3.29 A± 1.01

3.60 A± 1.33

2.66 A± 1.54

4.75 A± 1.11

FEF 25 %

5.30 A± 1.68

5.50 A± 1.54

4.60 A± 2.13

6.61 A± 1.73

FEF 50 %

3.78 A± 1.06

4.16 A± 1.22

3.30 A± 1.76

5.17 A± 1.32

FEF 75 %

2.01 A± 0.82

2.37A± 1.02

1.72 A± 1.12

3.12 A± 0.91

FEV 0.5/FVC %

63.74 A± 14.34

67.80 A± 15.11

59.42 A± 21.03

67.50 A± 23.02


85.70 A± 9.76

92.08 A± 8.77

79.96 A± 21.90

91.28 A± 11.14


98.20 A± 3.88

98.82 A± 4.55

96.76 A± 8.61

100 A± 0.00


100.62 A± 20.05

100.30 A± 22.58

92.74 A± 23.62

130.18 A± 26.28

Graph demoing intergroup comparing in average values of FVC, FEV 0.5, FEV 1, FEV 3 and PEFR

Graph demoing intergroup comparing in average values of FEF 25-75 % , FEF 25 % , FEF 50 % & A ; FEF 75 %

Graph demoing intergroup comparing in average values of FEV 0.5/FVC, FEV 1/FVC, FEV 3/FVC & A ; MVV


Statistically important diminution

FVC, FEV0.5, FEV1, FEV3 and FEF 50 % and FEF 25-75 % in petrol-pump workers.

Statistically undistinguished diminution

PEFR, MVV, FEF 25 % , FEF 75 % , FEV0.5/FVC, FEV1/FVC FEV3/FVC


The assorted lung map parametric quantities were recorded and compared between the topics and controls. In add-on, intergroup comparing of assorted lung map parametric quantities was done among topics on the footing of continuance of exposure.

FVC – Our findings are collateral with another study1,2 which reported statistically important diminution in FVC and found important relation between three exposure groups when compared with controls.

FEV 0.5 and FEV 1 – It is consistent with studies3,4, they showed reported statistically important diminution in FEV1 in gasoline pump workers with increasing old ages of exposure.

FEF 50 % – Our survey is in understanding with above surveies as they reported statistically important diminution in value of FEF 50 % .

PEFR- Our consequences are in understanding with the study5 which showed that average value of PEFR with old ages of exposure ( Group I & lt ; 5 old ages versus Group II & gt ; 5 old ages ) is statistically undistinguished. It may be due to the short continuance of exposure or a different statistical trial adopted for analysis.

FEF 25-75 % – The findings are same as the study4 which showed statistically important diminution. The consequence is in dissension with the work7 which showed statistically undistinguished alterations in FEFA­25-75 % during exposure to diesel fumes.


Any diminution in the lung maps with clip virtues attending despite the fact that the ascertained values may be within the normal scope, since it indicates likely morbidity in the event of go oning exposure to the piquing agent.

Since most persons are likely to stay symptomless boulder clay important pneumonic harm consequences, regular monitoring of lung map is desirable.

In order to forestall these alterations in gasoline make fulling workers, we suggest medical observation including pre-employment and periodic medical check-up like pneumonic map trials.

Early acknowledgment and remotion of susceptible workers from working topographic point before chronic damage develops will turn out to be good.


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